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Harvey Dent: You either die a hero or live long enough to see yourself become the villain
The Dark Knight

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2001: A Space Odyssey
HAL 9000: I know everything hasn't been quite right with me, but I can assure you now, very confidently, that it's going to be all right again. I feel much better now. I really do.
300
Xerxes: Consider the fate of your women.
Spartan King Leonidas: Clearly you don't know our women! I might as well have marched them up here judging by what I've seen.
300
King Leonidas: Madness...? This... is... Sparta!
A Few Good Men
Jessup: You don't want the truth because deep down in places you don't talk about at parties you want me on that wall - you need me on that wall. We use words like honor, code and loyalty. We use these words as the back-bone of a life spent defending something. You use them as a punchline.
About a Boy
Marcus: I used to want Will to marry my mom.
Ali: You serious?
Marcus: Yeah, but that was when she was depressed and I was desperate.
Will: Thanks, mate.
Ace Ventura
Ace: If I'm not back in five minutes - just wait longer!
Adaptation.
John Laroche: Who's gonna play me? I think I should play me.
Adaptation.
Robert McKee: The last act makes the film. Wow them in the end, and you've got a hit. You can have flaws, problems, but wow them in the end, and you've got a hit. Find an ending, but don't cheat, and don't you dare bring in a deus ex machina. Your characters must change, and the change must come from them. Do that, and you'll be fine.
Air Force One
President James Marshall: Get off my plane!
Airplane!
Rumack: How soon can you land this plane?
Captain Oveur: I can't tell.
Rumack: You can tell me, I'm a doctor.
Captain Oveur: No I mean I'm just not sure.
Rumack: Well, can't you take a guess?
Captain Oveur: Not for another two hours.
Rumack: You can't take a guess for another two hours?
Airplane!
Rumack: You've got to get these people to a hospital.
Elaine: A hospital? What is it?
Rumack: It's a big building with patients, but that's not important right now.
Aliens
Hudson: Vasquez, have you ever been mistaken for a man?
Vasquez: No... have you?